신진대사
5-클로로사이클린아마이드 및 5-플루오로사이클린아미드의 순식 및 트랜스 이종체는 체내에서 모두 대사에 의해 활성화된다.대사가 주로 간에서 발생하며, 간 세포 색소인 P450 효소의 작용을 통한다.이들 화합물로 형성된 대사산물은 알킬화 시약으로 DNA에 공모가로 결합해 DNA 복제를 방해하고 결국 세포사멸을 초래할 수 있다.
화학 원료를 구입해야하는 경우 요청 정보를 제출하여최신견적을받으십시오.
신진대사의 학술 논문
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5-Fluoro- and 5-chlorocyclophosphamide: Synthesis, metabolism, and antitumor activity of the cis and trans isomers
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1-Propanol, 3-amino-2-fluoro-
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Benzofuranones as potential antinociceptive agents: Structure-activity relationships
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3-[2-(4-bromophenyl)-2-oxo-ethyl]isobenzofuran-1(3H)-one
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The relationship between physicochemical properties, in vitro activity and pharmacokinetic profiles of analogues of diamine-containing efflux pump inhibitors
화학 물질
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(S)-N-1-BOC-4-CBZ-2-PIPERAZINECARBOXYLIC ACID 메틸 에스테르
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Carbon-14 labeling of a potential new immunoregulant agent
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4-(3',5'-dimethoxyphenyl)-1-(1-tetrahydrofuranyl)imidazole
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Structure-toxicity relationships of iodinated aromatic carbonates and related compounds
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10- (PARA-IODOPHENYL) -1- 운데 카놀
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Metabolism and metabolites of dithiocarbamates in the plant pathogenic fungus leptosphaeria maculans
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Nb-acetyl-2-indolylmethanamine
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Studies Related to Maytansinoids
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(3R,4R,5R)-3-benzoyloxy-4,5-dihydroxycyclohexanone 4,5-O-cyclohexylidene acetal
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Discovery of an Isothiazole-Based Phenylpropanoic Acid GPR120 Agonist as a Development Candidate for Type 2 Diabetes
화학 물질
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ethyl 3-(4-chlorophenyl)-5-methylisothiazole-4-carboxylate
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METABOLISM OF CHLOROPHENYLALANINES IN CROP AND WEED PLANTS IN RELATION TO THE FORMATION OF POTENTIAL HERBICIDAL END PRODUCTS
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2,3-Dichlorophenylacetic acid
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Transformation of arctiin to estrogenic and antiestrogenic substances by human intestinal bacteria
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(+/-)-trans-2-(3-benzyloxybenzyl)-3-<3-benzyloxy-α,α-bis(phenylthio)benzyl>butyrolactone
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Synthesis, cleavage, and antifungal activity of a number of novel, water-soluble ester prodrugs of antifungal triazole CS-758
화학 물질
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Acetic acid, hydroxy-, (4-methoxyphenyl)methyl ester
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