동물에 관한 연구
그런 다음 동물 모델에서 유망 화합물을 평가하여 체내에서의 유효성과 안전성을 평가합니다.이 단계는 항암제로서 이러한 화합물의 추가 개발 잠재력을 파악하는 데 필수적입니다.
화학 원료를 구입해야하는 경우 요청 정보를 제출하여최신견적을받으십시오.
동물에 관한 연구의 학술 논문
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Structure-based design, synthesis and biological testing of etoposide analog epipodophyllotoxin-N-mustard hybrid compounds designed to covalently bind to topoisomerase II and DNA
화학 물질
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4β-chloroacetamido-4-deoxy-4′-desmethylepipdophyllotoxin
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Design, synthesis, and biological evaluation of N-acetyl-2-(or 3-)carboxymethylbenzenesulfonamides as cyclooxygenase isozyme inhibitors
화학 물질
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4-fluoro-2-(methoxycarbonylmethyl)benzenesulfonamide
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Synthesis and biological evaluation of the pyrazole class of cyclooxygenase-2-inhibitors
화학 물질
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3-(4-chlorophenyl)-1-(4-nitrophenyl)-1H-pyrazole-4-carbaldehyde
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Identification of a novel fluoropyrrole derivative as a potassium-competitive acid blocker with long duration of action
화학 물질
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1-[5-(2-Fluoropyridin-3-yl)-1-(phenylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine fumarate
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Preparation and anti-inflammatory activities of diarylheptanoid and diarylheptylamine analogs
화학 물질
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3-Heptanone, 1,7-bis(4-hydroxy-3-methoxyphenyl)-
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Synthesis of new substance P analogues releasing histamine from rat peritoneal mast cells
화학 물질
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Boc-Pro-Lys(Z)-Pro-OCH3
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Synthesis and elastase-inhibiting activity of 2-pyridinyl-isothiazol-3(2H)-one 1,1-dioxides
화학 물질
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2-(6-chloropyridin-2-yl)-4,5,6,7-tetrahydro-1,2-benzoisothiazolium perchlorate
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Synthesis of arylidene-substituted gelastatin analogues and their screening for MMP-2 inhibitory activity
화학 물질
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E-3-(5-benzylidene-2-oxo-5,6-dihydro-2H-pyran-3-yl)propionic acid methyl ester
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anisaldehyde
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트리 에틸 아민
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Synthesis and evaluation of novel benzimidazole derivatives as antimicrobial agents
화학 물질
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N-(4-chloro-3-fluorophenyl)-2-(5-methoxy-1H-benzo[d]imidazol-2-ylthio)acetamide
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Metallocene-based inhibitors of cancer-associated carbonic anhydrase enzymes IX and XII
화학 물질
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4-(5-phenyl-1H-1,2,3-triazol-1-yl)benzenesulfonamide
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아민
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4- 디메틸 아미노 피리딘
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Development of new LXR modulators that regulate LXR target genes and reduce lipogenesis in human cell models
화학 물질
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4-(bromomethyl)-N-cyclohexyl-N-methylbenzenesulfonamide
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Design, synthesis, and biological evaluation of alcyopterosin a and illudalane derivatives as anticancer agents
화학 물질
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4-BroMo-5,7-diMethyl-2,3-dihydro-1H-inden-1-one
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Parallel synthesis of DAPT derivatives and their γ-secretase- inhibitory activity
화학 물질
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글리신, N-[(3,5- 디 플루오로 페닐) 아세틸] -L- 알라 닐 -2- 페닐-, (2S)-
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Design, synthesis, and biological evaluation of novel piperidine-4- carboxamide derivatives as potent CCR5 inhibitors
화학 물질
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tert-butyl 4-(4-cyanobenzylcarbamoyl)piperidine-1-carboxylate
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Rational discovery of a highly novel and selective mTOR inhibitor
화학 물질
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1-cyclopropyl-3-(4-(5-(2,2-difluoropropyl)-6a-methyl-6-oxo-5,6,6a,7,9,10-hexahydro[1,4]oxazino[3,4-h]pteridin-2-yl)phenyl)urea
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Synthesis and cytotoxicity studies of novel [1,2,4] Triazolo [1,5-a]pyrimidine-7-amines
화학 물질
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N-(3-chlorophenyl)-5-methyl-2-(3-((5-(morpholinomethyl)furan-2-yl)methylthio)propyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
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TVB-2640
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Synthesis of novel N-branched acyclic nucleoside phosphonates as potent and selective inhibitors of human, plasmodium falciparum and plasmodium vivax 6-oxopurine phosphoribosyltransferases
화학 물질
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diethyl 2-((2-hydroxyethyl)(2-(trityloxy)ethyl)amino)ethylphosphonate
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Silica gel
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Design, synthesis, and evaluation of imidazo[1,2-b]pyridazine derivatives having a benzamide unit as novel VEGFR2 kinase inhibitors
화학 물질
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N-[4-(imidazo[1,2-b]pyridazin-6-yloxy)phenyl]-N'-phenylurea
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5-(ω-aminoalkyl)aminoisoxazoles with hypertensive activity: Synthesis and screening of compounds with a sulfamide or carboxyl function at the end of the side chain
화학 물질
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N-Phenyl-N-<3-(4-chlorphenyl)-4-phenylisoxazol-5-yl>-aminoessigsaeure
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Design and synthesis of nonsteroidal progesterone receptor antagonists based on C,C′-diphenylcarborane scaffold as
ahydrophobic pharmacophore화학 물질
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1-(4-cyanophenyl)-2-(4-nitrophenyl)-1,2-dicarba-closo-dodecaborane
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Carbon-14 labeling of a potential new immunoregulant agent
화학 물질
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4-(3',5'-dimethoxyphenyl)-1-(1-tetrahydrofuranyl)imidazole
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Design, synthesis and evaluation of marinopyrrole derivatives as selective inhibitors of Mcl-1 binding to pro-apoptotic Bim and dual Mcl-1/Bcl-xL inhibitors
화학 물질
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(4,4′,5,5′-tetrachloro-1′H-1,3′-bipyrrole-2,2′-diyl)bis((5-chloro-2-hydroxy-4-methylphenyl)methanone)
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테트라 히드로 푸란
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아세토 니트릴
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Benzimidazole-derived ATP analogues as potential glutamine synthetase inhibitors
화학 물질
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1H- 벤즈 이미 다졸, 1- (2- 프로 페닐)-(9CI)
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