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폴리펩타이드 생체공학
폴리펩타이드 복제약은 펩타이드 구조와 기능을 시뮬레이션하도록 설계된 화합물이지만, 더 나은 약리적 특성을 가지고 있다.RGDR 시퀀스의 핵심 결합 베이스를 유지하면서 향상된 아키텍처 유연성을 제공하도록 설계될 수 있습니다.
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폴리펩타이드 생체공학의 학술 논문
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Conformationally flexible platelet aggregation inhibitors based on the tetrapeptide Arg-Gly-Asp-Arg
화학 물질
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N-α-[8-(nitroguanidino)octanoyl]aspartic acid amide β-benzyl ester
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Small-molecule inhibitors of the TLR3/dsRNA complex
화학 물질
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2-[[(2-플루오로페닐)설포닐]아미노]-3-페닐프로판산
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Antimicrobial activity of peptidomimetics against multidrug-resistant Escherichia coli: A comparative study of different backbones
화학 물질
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3-벤질아미노-프로피온산 tert-부틸 에스테르
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Asymmetric synthesis of propargylamines as amino acid surrogates in peptidomimetics
화학 물질
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ethyl 4-(3-oxoprop-1-yn-1-yl)benzoate
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Synthesis of chiral piperazinones as versatile scaffolds for peptidomimetics
화학 물질
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((2S,3R,4S,5R)-2-Benzyloxycarbonylamino-3,4,5,6-tetrahydroxy-hexylamino)-acetic acid methyl ester
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A novel green synthesis of α/β-amino acid functionalized pyrimidinone peptidomimetics using triazole ligation through click-multi-component reactions
화학 물질
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3-azido-N-[3-(4-bromophenyl)-1-(4-chlorophenyl)-3-oxopropyl]propanamide
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Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 3. Structure-activity studies of ketomethylene-containing peptidomimetics
화학 물질
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(R)-2-Benzyl-3-((S)-2-benzyloxycarbonylamino-3,3-dimethyl-butyryl)-succinic acid 4-tert-butyl ester 1-methyl ester
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Cyclopropane-derived peptidomimetics. Design, synthesis, and evaluation of novel enkephalin analogues
화학 물질
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N-[(1S-(1α,2α,1'α))-2-(2'-azido)ethan-1'-ol-cyclopropan-1-oyl]-L-phenylalanine-L-leucine
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Conformationally constrained CCK4 analogues incorporating IBTM and BTD β-turn mimetics
화학 물질
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(2S,5S,11bR,1'S)-2-[(Nα-(tert-butoxycarbonyl)-L-tryptophyl)amino]-5-[(1'-methoxycarbonyl-2'-phenyl)ethyl]carbamoyl-3-oxo-2,3,5,6,11,11b-hexahydro-1H-indolizino[8,7-b]indole
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Depsipeptides Featuring a Neutral P1 Are Potent Inhibitors of Kallikrein-Related Peptidase 6 with On-Target Cellular Activity
화학 물질
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N-(3-methyl-1-phenyl-1H-pyrazol-4-yl)amine
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