약효단
분자 중 그 생물학적 활성을 담당하며 특정 표적과 결합하는 부분.
화학 원료를 구입해야하는 경우 요청 정보를 제출하여최신견적을받으십시오.
약효단의 학술 논문
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Imidazo[1,2-a]pyridines that directly interact with hepatitis C NS4B: Initial preclinical characterization
화학 물질
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(3-chloro-6-furan-3-yl-8-trifluoromethyl-imidazo[1,2-a]pyridin-2-yl)-[3-(2-fluoro-phenyl)-pyrrolidin-1-yl]-methanone
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Development of progesterone receptor antagonists from 1,2-dihydrochromeno[3,4-f]quinoline agonist pharmacophore
화학 물질
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2'-fluoro-4-nitro-biphenyl-2-carboxylic acid
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Tuning the moenomycin pharmacophore to enable discovery of bacterial cell wall synthesis inhibitors
화학 물질
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phenyl 3,4,6-tri-O-acetyl-2-deoxy-1-thio-2-(2,2,2-trichloroethoxycarbonylamino)-β-D-glucopyranoside S-oxide
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Design, synthesis and protection against pentylenetetrazole-induced seizure of N-aryl derivatives of the phthalimide pharmacophore
화학 물질
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5-nitro-2-(2-phenylethyl)-1H-isoindole-1,3(2H)-dione
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Design, synthesis and identification of novel substituted 2-amino thiazole analogues as potential anti-inflammatory agents targeting 5-lipoxygenase
화학 물질
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Benzamide, N-[(diphenylamino)thioxomethyl]-4-nitro-
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Drug evolution concept in drug design: 1. Hybridization method
화학 물질
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2-diethylaminoethyl 4-amino-2-methoxybenzoate
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Derivatives of aryl amines containing the cytotoxic 1,4-dioxo-2-butenyl pharmacophore
화학 물질
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N-(2,6-다이메틸페닐)말레아믹산
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Novel inhibitors of bacterial two-component systems with gram positive antibacterial activity: Pharmacophore identification based on the screening hit closantel
화학 물질
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Phosphorane, [(3,4-dichlorophenyl)methylene]triphenyl-
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Structure-Activity Relationship Study of Ionotropic Glutamate Receptor Antagonist (2S,3R)-3-(3-Carboxyphenyl)pyrrolidine-2-carboxylic Acid
화학 물질
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(2S,3R)-3-(3-(benzyloxy)-5-carboxyphenyl)-1-(tert-butoxycarbonyl)-pyrrolidine-2-carboxylic acid
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DBU-Catalyzed Deconjugation of 7-Substituted 3,4-Didehydro-2-oxepanones. Deuterium Incorporation, Significance of the Imine Double Bond, and Application to the Synthesis of a Key Pharmacophore
화학 물질
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Cyclohexanecarboxylic acid, 2-oxo-1-(phenylmethyl)-, methyl ester
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1H-indole derivatives as calcium antagonists
화학 물질
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[3-(1-Hydroxy-propyl)-2-methyl-5-nitro-indol-1-yl]-phenyl-methanone
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Defining a minimum pharmacophore for simocyclinone D8 disruption of DNA gyrase binding to DNA
화학 물질
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3-amino-7-(benzyloxy)-2H-chromen-2-one
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Discovery of oxazole and triazole derivatives as potent and selective S1P1 agonists through pharmacophore-guided design
화학 물질
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N-(4-(4-bromophenyl)-1-hydroxy-2-(hydroxymethyl)butan-2-yl)acetamide
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Structure-activity relationships of 8-styrylxanthines as A2-selective adenosine antagonists
화학 물질
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(E)-N-(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl)-3-(3-fluoro-phenyl)-acrylamide
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