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HMG-CoA 환원효소
이 효소는 콜레스테롤의 생합성에 매우 중요한 역할을 하는 3-하이드록시-3-메틸글리세틸 코엔자임A(HMG-CoA) 환원효소다.그것은 콜레스테롤 생산의 핵심 단계인 HMG-CoA를 메톡시 카르복실산으로 변환하도록 촉매한다.
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HMG-CoA 환원효소의 학술 논문
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Inhibitors of cholesterol biosynthesis. 1. 3,5-dihydroxy-7-(N-imidazolyl)- 6-heptenoates and -heptanoates, a novel series of HMG-CoA reductase inhibitors
화학 물질
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(E)-7-[2-tert-Butyl-4,5-bis-(4-fluoro-phenyl)-imidazol-1-yl]-5-hydroxy-3-oxo-hept-6-enoic acid methyl ester
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SYNTHESIS OF A NOVEL HMG-COA REDUCTASE INHIBITOR
화학 물질
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Butanoic acid, 2-[bis(4-fluorophenyl)methylene]-3-methyl-, ethyl ester
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Inhibitors of Cholesterol Biosynthesis. 3. Tetrahydro-4-hydroxy-6-<2-(1H-pyrrol-1-yl)ethyl>-2H-pyran-2-one Inhibitors of HMG-CoA Reductase. 2. Effects of Introducing Substituents at Positions Three and Four of the Pyrrole Nucleus
화학 물질
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dimethyl 1-<2-(1,3-dioxolan-2-yl)ethyl>-2-(4-fluorophenyl)-5-(1-methylethyl)-1H-pyrrole-3,4-dicarboxylate
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Methyl 3-o-benzyl-2,4,6-trideoxy-6-iodo-α-D-erythro-hexopyranoside, a chiral synthon for the synthesis of inhibitors of HMG-CoA reductase
화학 물질
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methyl 3-O-benzyl-6-O-trityl-2-deoxy-α-D-ribo-hexopyranoside
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