IC50
생물학적 과정(이 경우 암세포의 증식)을 50% 억제하는 화합물 농도의 측정 단위입니다.
화학 원료를 구입해야하는 경우 요청 정보를 제출하여최신견적을받으십시오.
IC50의 학술 논문
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2-Amino-4-aryl thiazole: A promising scaffold identified as a potent 5-LOX inhibitor
화학 물질
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Ethanone, 1-[2-(methylphenylamino)-4-phenyl-5-thiazolyl]-
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Design, synthesis and identification of novel substituted 2-amino thiazole analogues as potential anti-inflammatory agents targeting 5-lipoxygenase
화학 물질
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Benzamide, N-[(diphenylamino)thioxomethyl]-4-nitro-
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Inhibition of human leukocyte elastase. 1. Inhibition by C-7-substituted cephalosporin tert-butyl esters
화학 물질
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(6R,7S)-3-Acetoxymethyl-7-benzyloxy-5,5,8-trioxo-5λ6-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid tert-butyl ester
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Integration of optimized substituent patterns to produce highly potent 4-aryl-pyridine glucagon receptor antagonists
화학 물질
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[4-(2-benzyloxy-4-fluoro-phenyl)-2,6-diisopropyl-5-vinyl-pyridin-3-yl]-methanol
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New highly active taxoids from 9β-dihydrobaccatin-9,10-acetals. Part 2
화학 물질
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C38H56O10Si
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Synthesis and evaluation of inhibitors of cytochrome P450 3A (CYP3A) for pharmacokinetic enhancement of drugs
화학 물질
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bis-N-[(S)-2-(pyrazol-4-ylmethoxycarbonylamino)-3-phenylpropyl]ethylamine
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A search for dual action HIV-1 reverse transcriptase, bacterial RNA polymerase inhibitors
화학 물질
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4-(4-methylphenyl)-3-(2-methylfuran-3-yl)-4,5-dihydro-1H-1,2,4-triazole-5-thione
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Phenethylthiazolylthiourea (PETT) compounds as a new class of HIV-1 reverse transcriptase inhibitors. 2. Synthesis and further structure-activity relationship studies of PETT analogs
화학 물질
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3-Ethoxy-2-fluoro-6-methoxyphenethylamine
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Synthesis, biological evaluation, and molecular modeling of nitrile-containing compounds: Exploring multiple activities as anti-Alzheimer agents
화학 물질
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2-[(3,4-Dimethyl-phenylamino)-methylene]-malononitrile
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Antiplasmodial metabolites isolated from the marine octocoral Muricea austera
화학 물질
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methyl-2',3',4'-tri-O-benzoyl-β-L-arabinopyranoside
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Synthesis and estrogen receptor affinity of 2,3-diarylindoles
화학 물질
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1H-Indol-5-ol, 2,3-diphenyl-
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Synthesis and xanthine oxidase inhibitory activity of 4,6-disubstituted 1-p-chlorophenylpyrazolo[3,4-d]pyrimidines
화학 물질
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1-(4-chlorophenyl)-4,6-dimethoxy-1H-pyrazolo[3,4-d]pyrimidine
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Sulfonyl fluoride inhibitors of fatty acid amide hydrolase
화학 물질
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1-(4-methoxyphenyl)-7-phenoxyheptane
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Synthesis and bioactivity of 3,5-dimethylpyrazole derivatives as potential PDE4 inhibitors
화학 물질
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5-(2,4-difluorophenyl)-2-furoyl chloride
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Synthesis of selected 3- and 4-arylcoumarin derivatives and evaluation as potent antioxidants
화학 물질
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5,7-diacetoxy-3-(3',4',5'-trimethoxyphenyl)-2H-1-chromen-2-one
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Novel pyrrolyl 2-aminopyridines as potent and selective human β-secretase (BACE1) inhibitors
화학 물질
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2- 피리딘 메탄 아민, 6- 아미노 - (9CI)
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Identification of novel ROS inducers: Quinone derivatives tethered to long hydrocarbon chains
화학 물질
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9-(phenylmethoxy)nonan-1-ol
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Synthesis and Protein-Tyrosine Kinase Inhibitory Activities of Flavanoid Analogues
화학 물질
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4H-1-Benzopyran-3-carboxylic acid, 4-oxo-2-(3,4,5-trimethoxyphenyl)-
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Design, synthesis and biological characterization of novel inhibitors of CD38
화학 물질
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1-[(2-benzyloxyethoxy)methyl]-3-aminocarbonylpyridinium chloride
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Synthesis and pharmacological properties of pyrazolotriazolopyrimidine derivatives
화학 물질
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1H-Pyrazole-4-carboxylic acid, 3-[[(phenylamino)thioxomethyl]amino]-, ethyl ester
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Synthesis and inhibitory action on HMG-CoA synthase of racemic and optically active oxetan-2-ones (β-Lactones)
화학 물질
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trans-4-heptyl-3-methyloxetan-2-one
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Synthesis of imidazothiazole-chalcone derivatives as anticancer and apoptosis inducing agents
화학 물질
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(E)-3-(6-(4-methoxyphenyl)imidazo[2,1-b]thiazol-5-yl)-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one
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Synthesis and antimalarial evaluation of 1, 3, 5-trisubstituted pyrazolines
화학 물질
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3-(4-ethoxy-3-methoxyphenyl)-1-(4-hydroxyphenyl)propenone
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Synthesis and evaluation of novel phenoxypropanolamine derivatives containing acetanilides as potent and selective β3-adrenergic receptor agonists
화학 물질
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(S)-4'-(2-{[2-hydroxy-3-(4-methylsulfonamidophenoxy)-propyl]amino}ethyl)-2-(2-pyridyl)acetanilide hydrochloride
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Selenoimidazolium Salts as Supramolecular Reagents for Protein Alkylation
화학 물질
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H-L-MESER-OH HCL
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Synthesis and antiplatelet activity of phenyl quinolones
화학 물질
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4-Oxo-7-phenyl-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester
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Design, synthesis, and biological evaluation of truncated deguelin derivatives as Hsp90 inhibitors
화학 물질
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2-(3,4-dimethoxyphenyl)-1-(5-methoxy-2,2-dimethyl-2H-chromen-6-yl)ethan-1-one
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Design, synthesis, and in vitro antiplatelet aggregation activities of ferulic acid derivatives
화학 물질
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(E)-3-(4-hydroxy-3-methoxyphenyl)-N,N-dimethylacrylamide
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Structural Requirements of Histone Deacetylase Inhibitors: SAHA Analogs Modified on the Hydroxamic Acid
화학 물질
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O-benzyl-N-(2-phenylethyl)hydroxylamine
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Design and modular parallel synthesis of a MCR derived α-helix mimetic protein-protein interaction inhibitor scaffold
화학 물질
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5-[이소시아노-(톨루엔-4-술포닐)-메틸]-벤조[1,3]디옥솔
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PK/PD Disconnect Observed with a Reversible Endothelial Lipase Inhibitor
화학 물질
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(SS,E)-N-(3-(3,4-dichlorophenyl)propylidene)-2-methylpropane-2-sulfinamide
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Design, synthesis, and structure-activity relationship studies of a potent PACE4 inhibitor
화학 물질
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tert-butyl 4-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)benzylcarbamate
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Anti-tumor activity of
anew series of benzoxazepine derivatives in breast cancer화학 물질
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methyl (S)-2-(N-(2-(benzyloxy)-4-methoxybenzyl)-4-methylphenylsulfonamido)-3-(4-(benzyloxy)phenyl)propanoate
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Novel lipoic acid analogues that inhibit nitric oxide synthase.
화학 물질
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N-{4-[(1,1-dimethylethoxy)carbonylamino]phenyl}-1,2-dithiolane-3-pentanamide
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1-Substituted vinyl-1-phthalanpropylamines as potential antidepressant agents.
화학 물질
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1,3-디히드로-3,3-디메틸-1-페닐이소벤조푸란-1-올
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Mercaptoamide-based non-hydroxamic acid type histone deacetylase inhibitors
화학 물질
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methyl 4-oxo-4-(phenylamino)butanoate
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A novel class of nonpeptidic biaryl inhibitors of human cathepsin K
화학 물질
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1-(4-BROMO-PHENYL)-4-METHYL-PIPERAZINE
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Design, synthesis, and biological evaluation of novel tetrahydroprotoberberine derivatives to reduce SREBPs expression for the treatment of hyperlipidemia
화학 물질
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10-methoxy-5,6,7,8,13,13a-hexahydro-2H-1,3-dioxolano[4,5-g]isoquinolino[3,2-a]isoquinolin-9-yl 4-fluorobenzenesulfonate
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Design, synthesis, and evaluation of orally active benzimidazoles and benzoxazoles as vascular endothelial growth factor-2 receptor tyrosine kinase inhibitors
화학 물질
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1-chloro-2-(2-chloro-ethoxy)-4-isothiocyanato-benzene
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