하이패스 필터링
하이패스 필터링 방법을 사용하여 라이브러리의 화합물이 AVP로 인한 혈관 수축에 길지 않은 능력을 가지고 있는지 테스트합니다.이것은 잠재적인 선도 화합물을 식별하는데 도움이 될 것이다.
화학 원료를 구입해야하는 경우 요청 정보를 제출하여최신견적을받으십시오.
하이패스 필터링의 학술 논문
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Design of potent and selective antagonists of the vasopressor responses to arginine-vasopressin
화학 물질
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3-MERCAPTO-3-METHYL-BUTYRYL-TYR-PHE-VAL-ASN-CYS-PRO-D-ARG-GLY-NH2
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Synthesis of 4-alkyl-, 4-aryl- and 4-arylamino-5-aminoisoquinolin-1-ones and identification of a new PARP-2 selective inhibitor
화학 물질
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1-methoxy-5-nitro-4-phenylisoquinoline
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Discovery of an in vivo chemical probe of the lysine methyltransferases G9a and GLP
화학 물질
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Methyl 5-Methoxy-2-nitro-4-(3-(pyrrolidin-1-yl)propoxy)benzoate
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Screening of a library of hemisalen ligands in asymmetric H-transfer: Reduction of aromatic ketones in water
화학 물질
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(2,6-dibromo-4-methoxyphenoxy)dimethylphenylsilane
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Improved, selective, human intestinal carboxylesterase inhibitors designed to modulate 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (irinotecan; CPT-11) toxicity
화학 물질
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N,N'-(1,4-phenylene)bis(2-fluorobenzenesulfonamide)
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피리딘
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Discovery of Novel and Potent Stearoyl Coenzyme A Desaturase 1 (SCD1) Inhibitors as Anticancer Agents
화학 물질
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3-피리다진카보닐 클로라이드, 1,6-디하이드로-6-옥소-(9CI)
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Isoxazolopyrimidines as novel F508-CFTR correctors
화학 물질
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4-isoxazolecarboxamide, 5-amino-3-(3-chlorophenyl)-
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Design, synthesis, and structure-activity relationships of novel insulin receptor tyrosine kinase activators
화학 물질
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4-methylphenyl 3-[({7-[({7-[({3-[(4-methylphenyl)oxysulfonyl]phenyl}amino)sulfonyl]-2-naphthyl}amino)carbonylamino]-2-naphthyl}sulfonyl)amino]benzenesulfonate
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5-Amino-2-chlorobenzoic acid
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Triphosgene
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Development of dimeric modulators for anti-apoptotic Bcl-2 proteins
화학 물질
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C26H24N2O6S4
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Diversity-oriented enantioselective synthesis of highly functionalized cyclic and bicyclic alcohols
화학 물질
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(-)-(S)-3-vinylcyclohex-2-en-1-yl benzoate
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Achiral oligoamines as versatile tool for the development of aspartic protease inhibitors
화학 물질
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bis[3-(benzenesulfonylamino)propyl]carbamic acid tert-butyl ester
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Diversity-oriented synthesis-facilitated medicinal chemistry: Toward the development of novel antimalarial agents
화학 물질
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4-fluoro-N-(((7R,8R,14S)-5-((2S)-1-((4-methoxybenzyl)oxy)propan-2-yl)-1,7,14-trimethyl-4-oxo-4,5,6,7,8,10,11,12,13,14-decahydro-1H-pyrazolo[3,4-b][1,9,5]dioxaazacyclotetradecin-8-yl)methyl)-N-methylbenzenesulfonamide
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Discovery of 2,5-diarylnicotinamides as selective orexin-2 receptor antagonists (2-SORAs)
화학 물질
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5-(3,5-dichlorophenyl)-N-(3,4-dimethoxybenzyl)-2,3'-bipyridine-3-carboxamide
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A novel route to synthesize libraries of quinoxalines via Petasis methodology in two synthetic operations
화학 물질
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2-(2-methoxyphenyl)-3-phenylquinoxaline
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Diversity oriented microwave-assisted synthesis of (-)-steganacin aza-analogues
화학 물질
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butyl-{1-[2'-(tert-butyldimethylsilanyloxymethyl)-4',5'-dimethoxybiphenyl-2-yl]-3-phenylprop-2-ynyl}-amine
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Structure Guided Lead Generation toward Nonchiral M. tuberculosis Thymidylate Kinase Inhibitors
화학 물질
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3-(3-페녹시-페닐)-프로판-1-OL
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Reaction discovery by using a sandwich immunoassay
화학 물질
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2-(4-((tert-butyldimethylsilyl)oxy)-3-methoxyphenyl)acetic acid
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Optimization of 5-phenyl-3-pyridinecarbonitriles as PKCθ inhibitors
화학 물질
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니코 티노 니트릴, 1,4- 디 하이드로 -4- 옥소-(6CI)
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Benzylidene ketal derivatives as M2 muscarinic receptor antagonists
화학 물질
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4-[4-(4-methoxy-benzenesulfonyl)-benzoyl]-[1,4']bipiperidinyl-1'-carboxylic acid ethyl ester
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Development of Small Molecules with a Noncanonical Binding Mode to HIV-1 Trans Activation Response (TAR) RNA
화학 물질
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3-amino-6-methyl-N-(3-(trifluoromethyl)phenyl)thieno[2,3-b]pyridine-2-carboxamide
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Identification of nonpeptidic small-molecule inhibitors of interleukin-2
화학 물질
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(3-{4-[5-(2,3-dichloro-phenyl)-2-methyl-2H-pyrazol-3-yl]-piperidine-1-sulfonylamino}-propyl)-carbamic acid tert-butyl ester
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Structure-cytotoxicity relationship of a novel series of miconazole-like compounds
화학 물질
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N-[2-(1H-imidazol-1-yl)-1-phenylethylidene]-N'-phenylhydrazine
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Pyrido<2,1-b>quinazolinecarboxamide Derivatives as Platelet Activating Factor Antagonists
화학 물질
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(R)-2-아미노-5-(3-피리딜)펜탄
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New oxadiazolidinedione derivatives as potent and selective human β3 agonists
화학 물질
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tert-butyl 2-{2,4-dioxo-5-[4-(4-oxo-1-piperidinyl)benzyl]-1,3-thiazolidin-3-yl}acetate
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Discovery of 8-Amino-imidazo[1,5-a]pyrazines as Reversible BTK Inhibitors for the Treatment of Rheumatoid Arthritis
화학 물질
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4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-N-(4-trifluoromethyl-pyridin-2-yl)benzamide
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Approaches to the high-throughput synthesis of analogues of dihydroaertiginoic acid
화학 물질
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L-Cysteine, N-(2-hydroxybenzoyl)-
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Structure-activity relationships of diphenylpiperazine N-type calcium channel inhibitors
화학 물질
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1- (o- 클로로 -α- 페닐 벤질) 피페 라진
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Parallel solid-phase synthesis of zatebradine analogues as potential If channel blockers
화학 물질
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7,8-Dimethoxy-3-(3-iodopropyl)-1,3-dihydro-2H-3-benzazepin-2-one
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Isoxazole carboxylic acids as protein tyrosine phosphatase 1B (PTP1B) inhibitors
화학 물질
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3-Isoxazolecarboxylic acid, 4-amino-5-[3-[(1E)-3-hydroxy-1-propenyl]phenyl]-, ethyl ester
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Small-molecular, non-peptide, non-ATP-competitive polo-like kinase 1 (Plk1) inhibitors with a terphenyl skeleton
화학 물질
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3,5-Difluoro-4-hydroxybenzeneboronic acid pinacol ester, 96%
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α-Hydroxy Phosphinyl-Based Inhibitors of Human Renin
화학 물질
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N-[(2S)-2-{[1-(cyclohexylmethyl)-2-(dimethoxyphosphoryl)-2-hydroxyethyl]amino}-4-methylpentanoyl]-Nalpha-(cyclopentylcarbonyl)-L-phenylalaninamide
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Selective inhibition of type II dehydroquinases
화학 물질
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3-deoxyquinic acid
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8-Substituted 3,4-dihydroquinolinones as a novel scaffold for atypical antipsychotic activity
화학 물질
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Benzoylcholine Chloride
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2,5,6-Trisubstituted imidazo[2,1-b][1,3,4]thiadiazoles: Search for antihyperlipidemic agents
화학 물질
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N-((2-(benzo[d][1,3]dioxol-5-yl)-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-5-yl)methylene)aniline
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Discovery of the First Environment-Sensitive Fluorescent Probe for GPR120 (FFA4) Imaging
화학 물질
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methyl 4-[(4-nitrophenyl)methoxy]benzenepropanoate
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Discovery of novel urea-based hepatitis C protease inhibitors with high potency against protease-inhibitor-resistant mutants
화학 물질
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N-(6-acetyl-3-methoxy-2-methylphenyl)-4-cyclopropylthiazole-2-carboxamide
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Structure-Activity Relationships of 9-Alkyladenine and Ribose-Modified Adenosine Derivatives at Rat A3 Adenosine Receptors
화학 물질
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9H-Purin-6-amine, 2-chloro-N-[(3-iodophenyl)methyl]-9-methyl-
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1H-indole derivatives as calcium antagonists
화학 물질
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[3-(1-Hydroxy-propyl)-2-methyl-5-nitro-indol-1-yl]-phenyl-methanone
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2-acetylphenol analogs as potent reversible monoamine oxidase inhibitors
화학 물질
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1-(4-(4-cyanobenzyloxy)-2-hydroxyphenyl)ethanone
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New benzimidazoles as thrombopoietin receptor agonists
화학 물질
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(E)-3-(4-Acetylamino-3-nitro-phenyl)-2-methyl-acrylic acid ethyl ester
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Identification of Darmstoff analogs as selective agonists and antagonists of lysophosphatidic acid receptors
화학 물질
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1,3-Dioxolane-4-methanol, 2-(8Z)-8-heptadecenyl-
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