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하이패스 필터링(HTS)
HTS는 비교적 짧은 시간 내에 칼륨 통로를 차단하는 다량의 화합물의 능력을 테스트하는 것과 관련된다.자동화와 로봇 기술은 종종 이 과정을 가속화하는 데 이용된다.
화학 원료를 구입해야하는 경우 요청 정보를 제출하여최신견적을받으십시오.
하이패스 필터링(HTS)의 학술 논문
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Identification of a novel fluoropyrrole derivative as a potassium-competitive acid blocker with long duration of action
화학 물질
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1-[5-(2-Fluoropyridin-3-yl)-1-(phenylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine fumarate
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Discovery of a novel small molecule agonist scaffold for the APJ receptor
화학 물질
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(2S)-cyclohexyl({[5-(2,6-dimethoxyphenyl)-1-(4-fluorophenyl)-1H-pyrazol-3-yl]carbonyl}amino)ethanoic acid
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Identification of a potent and selective free fatty acid receptor 1 (FFA1/GPR40) agonist with favorable physicochemical and in vitro ADME properties
화학 물질
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methyl 3-(4-((2-chloropyridin-4-yl)ethynyl)phenyl)propanoate
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Development of new LXR modulators that regulate LXR target genes and reduce lipogenesis in human cell models
화학 물질
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4-(bromomethyl)-N-cyclohexyl-N-methylbenzenesulfonamide
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Identification of arginine analogues as antagonists and agonists for the melanocortin-4 receptor
화학 물질
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(S)-2-TERT-BUTOXYCARBONYLAMINO-3-NAPHTHALEN-2-YL-PROPIONIC ACID METHYL ESTER
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Discovery and structural development of small molecules that enhance transport activity of bile salt export pump mutant associated with progressive familial intrahepatic cholestasis type 2
화학 물질
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methyl 3-{N-(1-butyl)-2-chloro-4-{[3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl]methoxy}benzamido}benzoate
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Synthesis of selective inhibitors against V. cholerae sialidase and human cytosolic sialidase NEU2
화학 물질
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methyl acetamido-2,6-anhydro-3,5-dideoxy-9-p-toluenesulfonyl-D-glycero-D-galactonon-2-enonate
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Identification of a potent small-molecule inhibitor of bacterial DNA repair that potentiates quinolone antibiotic activity in methicillin-resistant Staphylococcus aureus
화학 물질
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2-(4-{[(3-fluorophenyl)amino]carbonothioyl}-1-piperazinyl)-8-ethyl-5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid
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Identification of potent non-peptide somatostatin antagonists with sst3 selectivity
화학 물질
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2-tert-butoxycarbonylamino-3-(1H-indol-3-yl)-propionic acid 2-oxo-1,2-diphenyl-ethyl ester
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2,6-Disubstituted imidazo[2,1-b][1,3,4]thiadiazoles: Search for anticancer agents
화학 물질
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2-(2-fluorobiphenyl-4-yl)-6-phenylimidazo[2,1-b][1,3,4]thiadiazole
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Discovery of imidazopyridazines as potent Pim-1/2 kinase inhibitors
화학 물질
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(S)-tert-부틸 1-(3-a미노피리딘-4-일)피페리딘-3-일카르바메이트
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Rational discovery of a highly novel and selective mTOR inhibitor
화학 물질
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1-cyclopropyl-3-(4-(5-(2,2-difluoropropyl)-6a-methyl-6-oxo-5,6,6a,7,9,10-hexahydro[1,4]oxazino[3,4-h]pteridin-2-yl)phenyl)urea
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