베타 - 니코틴 아미드 모노 뉴클레오티드

기본 정보

• 표준명: 베타 - 니코틴 아미드 모노 뉴클레오티드
• CAS 레지스트리 번호: 1094-61-7
• 분자식: C11H15N2O8P
• 분자 무게: 334.222
• HS 코드: 2934999090
• Mol 파일: 1094-61-7.mol

동의어: Nicotinamide ribotide;[(2R,3S,4R,5R)-5-(3-Carbamoyl-1-pyridiniumyl)-3,4-dihydroxytetrahydro-2-furanyl]methyl hydrogen phosphate;1094-61-7 [RN];3-(Aminocarbonyl)-1-(5-O-phosphono-b-D-ribofuranosyl)pyridinium Hydroxide Inner Salt;3-Carbamoyl-1-[5-O-(hydroxyphosphinato)-β-D-ribofuranosyl]pyridinium [ACD/IUPAC Name];3-Carbamoyl-1-[5-O-(hydroxyphosphinato)-β-D-ribofuranosyl]pyridinium [German] [ACD/IUPAC Name];3-Carbamoyl-1-[5-O-(hydroxyphosphinato)-β-D-ribofuranosyl]pyridinium [French] [ACD/IUPAC Name];3-Carbamoyl-1-b-D-ribofuranosylpyridinium Hydroxide 5′-(Dihydrogen Phosphate) Inner Salt;Pyridinium,3-(aminocarbonyl)-1-(5-O-phosphono-β-D-ribofuranosyl)-, inner salt [ACD/Index Name];pyridinium, 3-(hydroxyiminomethyl)-1-(5-O-phosphono-β-D-ribofuranosyl)-, inner salt;3-(aminocarbonyl)-1-(5-O-phosphono-b-D-ribofuranosyl)-Pyridinium hydroxide inner salt;3-(aminocarbonyl)-1-(5-O-phosphono-b-D-ribofuranosyl)-Pyridinium inner salt;3-(aminocarbonyl)-1-(5-O-phosphono-β-δ-ribofuranosyl)-Pyridinium hydroxide inner salt;3-(aminocarbonyl)-1-(5-O-phosphono-β-δ-ribofuranosyl)-Pyridinium inner salt;3-Carbamoyl-1-b-D-ribofuranosylpyridinium hydroxide 5′-phosphate inner salt;3-Carbamoyl-1-β-δ-ribofuranosylpyridinium hydroxide 5′-phosphate inner salt;b-D-NMN;b-NMN;Nicotinamide ribonucleoside 5′-phosphate;β-δ-NMN;((2R,3S,4R,5R)-5-(3-Carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogen phosphate;??-Nicotinamide mononucleotide;?-Nicotinamide Mononucleotide;?-NMN;[(2R,3S,4R,5R)-5-(3-aminocarbonylpyridin-1-ium-1-yl)-3,4-dihydroxy-oxolan-2-yl]methyl hydrogen phosphate;[(2R,3S,4R,5R)-5-(3-carbamoyl-1-pyridin-1-iumyl)-3,4-dihydroxy-2-tetrahydrofuranyl]methyl hydrogen phosphate;[(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate;[(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl hydrogen phosphate;¦Â-Nicotinamide mononucleotide;1-[(2R,3R,4S,5S)-3,4-dihydroxy-5-[(hydroxy-oxido-phosphoryl)oxymethyl]oxolan-2-yl]pyridine-5-carboxamide;1-[(2R,3R,4S,5S)-3,4-dihydroxy-5-[(hydroxy-oxido-phosphoryl)oxymethyl]tetrahydrofuran-2-yl]pyridine-5-carboxamide;3-(aminocarbonyl)-1-(5-O-phosphonato-β-D-ribofuranosyl)pyridinium;3-(aminocarbonyl)-1-(5-O-phosphono-?-D-ribofuranosyl)-pyridinium, inner salt;3-(aminocarbonyl)-1-(5-O-phosphono-β-D-ribofuranosyl)pyridinium, inner salt;3-(aminocarbonyl)-1-[5-O-(hydroxyphosphinato)-β-D-ribofuranosyl]pyridinium;3570187 [Beilstein];3-carbamoyl-1-[(2R,3R,4S,5R)-5-[(hydrogen phosphonatooxy)methyl]-3,4-dihydroxyoxolan-2-yl]-1λ5-pyridin-1-ylium;3-carbamoyl-1-[(2R,3R,4S,5R)-5-[(hydrogen phosphonatooxy)methyl]-3,4-dihydroxyoxolan-2-yl]-1λ5-pyridin-1-ylium;3-carbamoyl-1-β-D-ribofuranosylpyridinium hydroxide 5′-(dihydrogen phosphate) inner salt;B-NICOTINAMIDE MONONUCLEOTIDE;EINECS 214-136-5;MFCD00038748;Nicotinamide D-ribonucleotide;nicotinamide mononucleotide;Nicotinamide nucleotide;Nicotinamide ribonucleotide;Nicotinamide-1-ium-1-β-D-ribofuranoside 5′-phosphate;NMN;NMN zwitterion;UNII:2KG6QX4W0V;UNII-2KG6QX4W0V;β-Nicotinamide D-ribonucleotide;β-Nicotinamide mononucleotide;β-NICOTINAMIDE MONONUCLEOTIDE[4-3H(N)];β-Nicotinamide ribonucleotide;β-Nicotinamide ribose monophosphate;β-NICOTINAMIDEMONONUCLEOTIDE;β-NMN

관련 CAS 번호: 1000017-93-5 1000017-94-6 1000017-95-7 1000017-98-0 1000018-03-0 1000018-06-3 1000018-13-2 1000018-17-6 1000018-21-2 1000018-25-6

표준명의 화학적 성질

물리적 데이터:

안전정보:

• 픽토그램:
• 위험 코드:
• 진술:
• 안전 선언문:

사용:

• 소개 및 적용: 베타-니코틴아민드 모노뉴클레오티드(NMN)는 RNA 어팜퍼와 리보즘 활성화 과정에서 β-NMN 활성화된 RNA 조각을 연구하는 데 사용됩니다. NMN은 라이보스와 니코틴아민드에서 파생된 핵산으로, 니코틴아민드(니코틴)는 비타민 B3의 파생물로 알려져 있습니다. NAD+의 생화학적 전구물로서, 펠라그라 예방에 유용할 수 있습니다. NMN은 니코틴 아데린 디뉴클레오티드(NAD+)의 생합성 중간 단계로, Nampt는 니코틴아민드와 5-인산화 라이보스-1-파이로포스포닌을 융합하여 β-NMN을 생성하고, β-NMN 아데닌트랜스펜타제로 NAD+로 전환됩니다. 50-100 μM 농도에서는 NMN은 Nampt+/- 마우스 모델의 NAD 생합성과 혈당 자극 인슐린 분비를 증진시키며, 500 mg/kg/day 투여량에서는 고지방 식이로 인한 2형 당뇨병 마우스의 혈당 인도를 개선하며, NAD+ 수준을 복원합니다. NMN은 RNA 어팜퍼 내의 결합 모터와 β-NMN 활성화된 RNA 조각을 포함한 리보즘 활성화 과정을 연구하는 데 사용되며, NMN은 NAD+ 수준을 복원하고 2형 당뇨병 마우스의 혈당 인도를 개선하는 등의 역할을 수행합니다.