트리플루오로메탄술폰산디플루오로메틸에스테르

기본 정보

• 표준명: 트리플루오로메탄술폰산디플루오로메틸에스테르
• CAS 레지스트리 번호: 1885-46-7
• 분자 무게: 200.086
• HS 코드: 2905190098
• Mol 파일: 1885-46-7.mol

동의어: 디플루오로메틸트리플레이트

관련 CAS 번호: 1065092-89-8 187100-75-0 1189858-70-5 18398-80-6 1644-85-5 1221288-23-8 13223-03-5 13653-62-8 1072952-02-3 154464-26-3

표준명의 화학적 성질

물리적 데이터:

안전정보:

• 픽토그램: C,Xn
• 위험 코드: C,Xn
• 진술: R22-R34
• 안전 선언문: S26-S36/37/39-S45

사용:

• 소개 및 적용: Difluoromethyl triflate (TfO-CHF2) is a useful reagent for various difluoromethylation reactions, including the preparation of difluoromethoxylated heterocycles from hydroxylated N-based heterocycles, and the synthesis of trifluoromethylated arenes using diaryliodonium salts in the presence of copper and TBAT. It also allows for a simple method to prepare difluoromethyl ethers and thioethers from alcohols and thiols under basic conditions. Additionally, difluoromethyl phenols can be obtained in a single pot from boronic acids and C-H activation of arenes. This reagent is easy to handle, air-stable, and non-ozone-depleting, and can be synthesized by reacting TMSCF3 and triflic acid in the presence of TiCl4.