ABT-492 메글루마인

기본 정보

• 표준명: ABT-492 메글루마인
• CAS 레지스트리 번호: 352458-37-8
• 분자식: C25H30ClF3N5O8
• 분자 무게: 635.982
• Mol 파일: 352458-37-8.mol

동의어: ABT 492 MegluMine;ABT492 MegluMine;ABT-492 MegluMine;Delafloxacin (MegluMine);ABT-492MegluMine/ABT492MegluMine;(2R,3R,4R,5S)-6-(MethylaMino)hexane-1,2,3,4,5-pentaol 1-(6-aMino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylate;(2R,3R,4R,5S)-2,3,4,5-tetrahydroxy-6-(MethylaMino)hexyl 1-(6-aMino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylate;(2R,3R,4R,5S)-2,3,4,5-Tetrahydroxy-6-(methylamino)hexyl 1-(6-amino-3,5-difluoropyridin-2-yl)-8

관련 CAS 번호: 35467-98-2 39984-17-3 304-52-9 37224-00-3 394704-97-3 32187-15-8 344764-39-2 309739-67-1 302967-87-9 31814-68-3

표준명의 화학적 성질

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사용:

• 소개 및 적용: Delafloxacin meglumine (ABT-492) is a broad-spectrum antibiotic that is effective in treating various types of bacterial infections. It belongs to the anionic fluoroquinolone class of antibiotics and has a unique chemical structure that enhances its potency in acidic environments. Delafloxacin works by inhibiting DNA replication and repair by targeting DNA gyrase and topoisomerase IV. It can be administered orally or parenterally and has potent activity against methicillin-resistant Staphylococcus aureus (MRSA) and Streptococci, as well as Enterobacteriaceae and Pseudomonas aeruginosa. The drug was approved by the FDA in June 2017 for the treatment of acute bacterial skin and skin structure infections based on data from two phase III trials.