테 노포 비어 디 소프 록실 푸마 레이트

기본 정보

• 표준명: 테 노포 비어 디 소프 록실 푸마 레이트
• CAS 레지스트리 번호: 202138-50-9
• 분자식: C23H34N5O14P
• 분자 무게: 635.522
• HS 코드: 2933599550
• Mol 파일: 202138-50-9.mol

동의어: 테노포비르 디소프록실 푸마르산염테노포비르 디소프록실 푸마르산염(R)-(((1-(6-아미노-9H-퓨린-9-일)프로판-2-일옥시)메틸)포스포릴)비스(옥시)비스(메틸렌)이소프로필 디카르보네이트 푸마르산염2-( 아데닌-9-일)-1-(R)-메틸-에톡시메틸포스폰산 비스(이소프로폭시카르보닐옥시메틸)에스테르 푸마레이트9-[(R)-2-[[비스[[(이소프로폭시카르보닐)옥시]메톡시]포스피닐]메톡시]프로필]아데닌 푸마르산염9-[2-(R)-[[비스[[(이소프로폭시카르보닐)옥시]메톡시]포스피노일]메톡시]프로필]아데닌 푸마르산염9-[(R)-2-[[비스[[(이소프로폭시카르보닐)옥시]메톡시] 포스피닐]메톡시]프로필]아데닌 푸마르산염

관련 CAS 번호: 25699-82-5 215649-70-0 261723-32-4 28129-52-4 206748-69-8 27907-06-8 215649-72-2 2346-44-3 22528-67-2 21962-84-5

표준명의 화학적 성질

물리적 데이터:

안전정보:

• 픽토그램: Xi
• 위험 코드: Xi
• 진술: 36/37/38
• 안전 선언문: S26; S36

사용:

• 소개 및 적용: Tenofovir disoproxil fumarate (Viread) is a nucleotide-analogues antiretroviral drug developed by Gilead Sciences, which acts as a reverse transcriptase inhibitor (nRTI) to block viral production in HIV-infected people. It is the first nucleotide reverse transcriptase inhibitor used for the treatment of HIV infection and is also used for the treatment of chronic hepatitis B virus (HBV) infection in adults and children aged 12 and older. Tenofovir disoproxil fumarate is a water-soluble diester prodrug that is rapidly hydrolyzed in vivo to form the free tenofovir, which acts as a potent competitive inhibitor for reverse transcriptase. The drug is eliminated by the kidney, is not metabolized by the liver, and is not associated with P450 interactions. It is generally used in combination with other medicines, and its efficacy is enhanced when taken with food. Tenofovir disoproxil has shown to be effective against 3TC-resistant HIV strains and has a long intracellular half-life, allowing for once-daily dosing.